High priority & Special Synthesis Projects
• Novel Drug Prototypes
• Scaled Intermediates (scaffolds)
• Reference Standards
• Process Chemistry
• Small Focused Libraries (10 - 100 compounds)
• Organic Materials for Solar Cells & Transistors
• Fluorophores & Light Emitting Polymeric Organics
NMR Station
Purification Station 313A
Typical 5L Reaction
Typical 22 L Reaction
Benefits of Smaller CRO
• Highly Focused Chemists
• Projects Completed Faster
• Lower Cost For High Quality Work
• High Quality Output
• No Effort Dilution
Chemical Development & Optimization
• Large & Small Scale
• Design of New Procedures
• New Polymorphs & Analysis
• Patent Experimental Validation
Custom Building Block Examples
Piperazine Amino Acid Production
Custom Orthogonal Protection Strategies
Piperidine α Amino Acids
Click structure for other examples
Pyrrolidine α Amino Acids
Click structure for other examples
Unnatural-αα-disubstituted Amino Acids
Suitably protected for Protein Engineering
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Rapid-Turnaround Synthesis
• Projects Commence in 24-48 hrs
• Quotations in 24 hrs
• Known & Unknown Compounds
• Most Competitive Rates
• Result Driven
Est. 1997 in Research Triangle Park, NC
Experience and Cost Containment
Many larger " impressive companys" can be
costly and less efficient. Frequently the chemists
are inundated with multiple projects causing
a dilution of attention and focus needed for
successful outcomes.
MonomerChem Inc has a long history of:
•No disappointing teleconferences
•No disappointing reports
•No excuses
•Just results
This is because Monomerchem Chemists have
all been trained by large pharma (Pfizer, Glaxo &
Burroughs Wellcome) and have routinely synthesized
and purified a vast array of both novel and known
compounds.
NON PROPRIETARY EXAMPLES
(click on structure for details)
(+)-9-O-Desmethyl-α-dihydrotetrabenazine
2'-Fl-2'-deoxy-Nicotinamide
Arabino mononucleotide
Nonproprietary improved multi-gram prep
by Custom Synthesis Inc
SR 141716 constrained analogs
Improved multi-gram prep
by MonomerChem Inc
Ibudilast combi-chem scaffold
Example of a large scale preparation
of high energy intermediates
Novel Analogs of Reference Stds
New TAK-536 analogs
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Over 14 Years Serving The Pharmaceutical,
BioTech, & Electronic Engineering Industries including:
•Major Universities
•Major Pharmaceutical Companies
•Major Engineering Companies
•Federal Agencies
•BioTech Start-Ups
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