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MONOMERCHEM LABORATORIES, P.O. Box 12564, RTP, North
Carolina
We perform inexpensive custom synthesis of complex organic compounds. The custom synthesis of organics
can be performed by a variety of individuals. The cost however depends on how experienced the chemist actually is.
If the chemist is a reproduction chemist and is attempting to veer away from an experimental protocol
then the result will often be a bad custom synthesis operation. Promises of low cost for a custom synthesis
is only a promise which can only be realized by the final delivery of the compound. We perform
the custom synthesis of heterocycles, carbocycles, peptides, organic intermediates, Positron Emission Tomography
intermediates and standards. We perform the custom synthesis of analytical reference standards and the
custom synthesis of GMP starting materials. To perform a custom synthesis, many chemists require
experimental protocols or references to the synthetic material in the past. We do not require any
experimental reference material for any thermodynamically stable molecule in order to perform a custom synthesis.
We conduct our own literature searches for a variety or organic transformations before quoting on
a custom synthesis request so that we are highly confident that we can actually deliver a product
on the quoted timeline. It may seem that outsourcing to asia in inexpensive at first; but much of the chemistry
that we do here is optimization and creativity oriented custom synthesis work. Having years
of experienced chemists and a wealth or knowledge with respect to problem solving skills in custom synthesis
is what you get by interacting with monomerchem inc and custom synthesis inc. Imagine for example that you
need the synthesis of a compound very similar to an existing drug but have no protocol for its
custom synthesis. We routinely do this kind of work and we do it rapidly. We would rather generate an
answer for our clients rather than a report full of excuses as to why the compound has not yet
been produced. The custom synthesis of carbocycles and enantiopure or chiral compounds is also
something that we routinely do. We begin by designing the synthesis of the enantiopure compound either by
utilizing asymmetric synthesis or by a resolution technique; either way the compounds are delivered
rapidly and efficiently. We perform the custom synthesis of heterocycles as well. The synthesis
of a variety of heterocycles and a variety of chemically challenging compounds is routine work
at monomerchem inc.